Bioimpedance spectroscopy can precisely discriminate human breast carcinoma from benign tumors

Bioimpedance spectroscopy can precisely discriminate human breast carcinoma from benign tumors

Intraoperative frozen pathology is critical when a breast tumor is not diagnosed before surgery. However, frozen tumor tissues always present various microscopic morphologies, leading to a high misdiagnose rate from frozen section examination. Thus, we aimed to identify breast tumors using bioimpedance spectroscopy (BIS), a technology that measures the tissues' impedance. We collected and measu...

Evaluation of a new 99mTc-Bombesin analog in differentiation of malignant from benign breast tumors

Introduction: The gastrin releasing peptide (GRP) receptor is over expressed in a variety of common human tumors. Radiolabeled bombesin analogues have exhibited high binding affinity for these receptors. The aim of this study was to assess the value of a new 99mTc-bombesin analog in the differentiation of malignant from benign breast tumors. Methods: 99mTc-bombesin scans ...

Human in-vivo 31P MR Spectroscopy of Benign and Malignant Breast Tumors

OBJECTIVE To assess the potential clinical utility of in-vivo 31P magnetic resonance spectroscopy (MRS) in patients with various malignant and benign breast lesions. MATERIALS AND METHODS Seventeen patients with untreated primary malignant breast lesions (group I), eight patients with untreated benign breast lesions (group II) and seven normal breasts (group III) were included in this study. ...

Bioimpedance Spectroscopy

In the context of biology, electrical phenomena are usually identified with ionic currents through protein channels, for example as they are postulated during nerve signalling (Andersen et al. Prog Neurobiol 88(2):104–113, 2009; Sakmann and Neher Annu Rev Physiol 46:455–472, 1984). However, there are more electrical phenomena that play a significant role in biological systems, namely those aris...

Benign Tumors of the Breast